Relationship of concentration and risk quotient (RQ) of benzene, toluene and xylene (BTX) with Malondialdehyde (MDA) levels and neurotoxic risk in workers exposed to BTX in Surabaya

Benzene, toluene and xylene (BTX) are organic solvents that can cause neurotoxic effects on The body of workers exposed to these materials. Therefore, this study aims to determine the relationship between BTX concentration and RQ with MDA levels and neurotoxic risk in workers exposed to BTX in five industries in Surabaya. This research was conducted in five industries in Surabaya that use BTX as a solvent in the production process. This industry is located in Osowilangun, Ketintang, Jemursari, Kalijudan and AUP. The research design used was Cross Sectional with a total sample of 69 people. The variables studied included BTX concentration, RQ benzene, MDA levels, and neurotoxic risk. Data were analyzed using the Spearman correlation test. There was no significant relationship between benzene and xylene concentration and RQ with MDA levels and neurotoxic risk in the sample (p> 0.05). There was no significant relationship between BTQ RQ and MDA levels in the sample (p> 0.05). There was no significant relationship between BTX concentration and neurotoxic risk in the sample (p> 0.05). There was a significant relationship between Toluene concentration and MDA levels in the sample (p <0.05). There was a significant relationship between Toluene RQ and MDA with neurotoxic risk in the sample (p <0.05). There was no significant relationship between RQ BTX with MDA, BTX concentration and neurotoxic risk, and RQ benzene and xylene with neurotoxic risk in workers in five industries in Surabaya. Nevertheless, there was a significant relationship between RQ Toluene with neurotoxic risks and between MDA and neurotoxic risk in workers in five industries in Surabaya.