Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun Shoe home industry workers

Ningrum, Diah Pramesthi and Tualeka, Abdul Rohim and Jalaludin, Juliana and Russeng, Syamsiar S. and Rahmawati, Pudji and Ahsan, Ahsan and Susilowati, Indri H (2020) Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun Shoe home industry workers. Indian Journal of Forensic Medicine & Toxicology, 14 (4). pp. 868-932.

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Abstract

Introduction: Exposure of toluene can cause a decrease in glutathione concentration, increase in malondialdehyde and neurotoxic symptoms. The safe duration of toluene in hours/day for each person can vary. The purpose of this study is to determine the relationship between the safe duration of toluene (hours/day) with the concentration of glutathione, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers. Methods: This research was observational with quantitative approach and cross-sectional design. The sampling technique used was accidental sampling with 25 respondents. The variables studied were safe toluene duration (hours/day), glutathione concentration, malondialdehyde concentration, and neurotoxic symptoms. Data were analyzed using Pearson and Phi correlation. Result: The average of safe duration was 1,489 hours/day, glutathione concentration was 58,349 µg/L, and malondialdehyde was 7,847 MU. As many as 11 out of 14 workers experienced neurotoxic symptoms. The relationship between safe duration (hours/day) with glutathione concentration (r=0.139) and malondialdehyde (r=-0.146) was very weak. While, the relationship between safe duration (hours/day) and neurotoxic symptoms was weak (φ=-0.223). Conclusion: The relationship between safe duration in hours/day with glutathione concentration and malondialdehyde was very weak, while relationship with neurotoxic symptoms was weak.

Item Type: Article
Creators:
Creators
Email
NIDN
Ningrum, Diah Pramesthi
UNSPECIFIED
UNSPECIFIED
Tualeka, Abdul Rohim
abdul-r-t@fkm.unair
UNSPECIFIED
Jalaludin, Juliana
UNSPECIFIED
UNSPECIFIED
Russeng, Syamsiar S.
UNSPECIFIED
UNSPECIFIED
Rahmawati, Pudji
pudji.rahmawati@uinsby.ac.id
2025036703
Ahsan, Ahsan
UNSPECIFIED
UNSPECIFIED
Susilowati, Indri H
UNSPECIFIED
UNSPECIFIED
Subjects: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111708 Health and Community Services
Divisions: Fakultas Dakwah dan Komunikasi > Pengembangan Masyarakat Islam
Depositing User: Pudji Rahmawati
Date Deposited: 12 Apr 2023 02:45
Last Modified: 12 Apr 2023 02:45
URI: http://repository.uinsa.ac.id/id/eprint/3027

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